In today’s world, beer has become an integral part of our social lives. It’s not just a beverage; it’s a social lubricant, bringing people together and facilitating communication.
However, we all have that one friend who can down pint after pint without showing any signs of intoxication, while others turn “quắc” after a single sip. So, what’s the science behind this phenomenon? Let’s explore the reasons together!
1 The Role of Enzymes ADH – ADLH and CYP P450
According to Dr. Nguyen Trung Cap, Head of the Emergency Department at the Central Tropical Diseases Hospital, our bodies possess two types of enzymes that are responsible for metabolizing beer: ADH – ALDH and CYP P450. ADH converts ethanol into acetaldehyde, which is then transformed by ALDH into acetic acid, providing energy for our bodies. However, when we consume excessive amounts of alcohol, the ADH-ALDH system becomes saturated, prompting the CYP P450 system to kick in and assist.
Enjoying beer with friends
Consequently, individuals who drink beer regularly exhibit higher CYP P450 activity, resulting in a greater capacity to metabolize alcohol compared to occasional drinkers. Additionally, one’s physical constitution and health play a role in the efficiency of these enzyme systems.
Beer is absorbed in the stomach and small intestine, so the rate of absorption depends on the alcohol content of the beer and the presence or absence of food in the stomach. The type of food consumed can also influence the absorption process.
Dr. Nguyen Trung Nguyen, Head of the Toxicology Center at Bach Mai Hospital, adds that higher blood alcohol levels are associated with increased consumption. Furthermore, drinking on an empty stomach leads to faster absorption and quicker intoxication.
Further reading: Tips to stay sober and quick recovery during parties
2 Gender and Physical Build Matter, Too
Professor Peter Martin, a psychiatrist and behavioral scientist at Vanderbilt University Medical Center, weighs in on the discussion, noting that drinking capacity is influenced by gender and physical build. Generally, men with larger physiques tend to have higher alcohol tolerance compared to women or individuals with smaller frames.
Alcohol tolerance varies with gender and physical build
Nonetheless, a high alcohol tolerance does not equate to good health. Excessive drinking, regardless of tolerance, can impair the senses and wreak havoc on the body, increasing the risk of liver, brain, nerve, spinal cord, stomach inflammation, and cancer, among other ailments.
Therefore, it’s essential to drink in moderation and only when necessary. Just because you can handle your liquor doesn’t mean it’s healthy to do so. Excessive drinking can be detrimental to your well-being.
Tip: 7 effective tips to avoid getting drunk while drinking
Now you know why some people seem immune to intoxication while others turn “quắc” instantly. We hope this knowledge empowers you to make healthier choices and protect your well-being. Stay informed and stay healthy!
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