Nocturia
The most telling sign that your kidneys are in distress is nocturia, or frequent urination at night. On average, a healthy person should only need to urinate once during the night, if at all. However, if you find yourself getting up 3 to 4 times, or feeling like you haven’t fully emptied your bladder, it could indicate a decline in your kidney function. When kidney function decreases, the body struggles to concentrate and retain urine, leading to uncontrolled urination at night.

Edema and Periorbital Edema in the Evening
If you experience normal mobility during the day but notice swelling and heaviness in your legs or puffiness around your eyes in the evening, it’s time to take action. This condition, known as edema, occurs when the kidneys fail to filter and excrete excess salt and fluid from the body, leading to a buildup in the tissues. It is a clear indicator of early-stage kidney failure, and you should seek medical attention as soon as possible.
Insomnia or Restless Sleep
As kidney function declines, blood filtration becomes disrupted, allowing toxins to accumulate in the body. This buildup of toxins affects the central nervous system, resulting in difficulty falling asleep, restless sleep, and frequent awakenings during the night. Prolonged insomnia not only leaves you feeling exhausted but also exacerbates kidney issues, creating a dangerous cycle.
Evening Back Pain or Flank Pain
Kidney problems can manifest as back pain or flank pain in the evening. A dull ache in the lower back or sides towards the end of the day should not be ignored. When the kidneys are inflamed or damaged, the nerves in this area may become stimulated, causing pain. However, many people mistake this pain for simple joint pain or nerve pain and don’t seek medical attention until it’s too late.

Prolonged Fatigue and Lassitude
When kidney function declines due to illness, the body may not produce enough erythropoietin, a hormone that stimulates the bone marrow to produce red blood cells. As a result, the body becomes anemic, leading to fatigue, exhaustion, and lassitude even without strenuous activity. In the evening, after a day of activity, this fatigue is even more pronounced, leaving you feeling weak and limp. If you consistently feel drained, short of breath, and lacking in energy each evening, it could be a sign that your kidneys are in trouble.
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