Visiting the DNA Analysis and Genetic Technology Center in Hanoi, Mr. N.D.D (31 years old, residing in Hoai Duc, Hanoi) revealed that he and his wife have two children, a 5-year-old boy and a 3-year-old girl.
For the past 3 years, he has always wondered about the identity of his son. Because his son’s appearance is different from both his father and mother. Mr. D. even jokingly refers to himself as “a family with curly hair for three generations, but the hair of the son is straight, golden like a Westerner.” The couple have dark skin, but the son has white skin and blonde hair. Many times, neighbors and friends have teased him, saying “looks like a Westerner,” which makes him very uncomfortable.
Mr. D.’s wife saw her husband sad because their son doesn’t resemble anyone, and she expressed her annoyance, affirming many times that “if I hadn’t mistaken it at birth, then that is definitely our child.”
Customers come to the DNA testing center. Photo: CGAT.
Bringing their son’s hair to the testing center, the results confirmed 99.9999% that the two share a father-son bloodline. However, according to Master Nguyen Thi Nga, Director of the DNA Analysis and Genetic Technology Center in Hanoi, in the testing application, this man registered for DNA testing for his son and the alleged father, but the testing sample turned out to be for the father and daughter. Mrs. Nga stated that the child possesses the XXY chromosome, while the boy’s chromosome should be XY. The excess X chromosome may be due to the boy having Klinefelter syndrome.
Upon hearing Mrs. Nga’s advice, Mr. D. became worried and immediately returned to tell his wife. The couple brought their son directly to the center. This time, they did a blood test with the fastest results in just 4 hours. Mrs. Nga shared that the results remained the same, confirming the father-son bloodline, but the child is a girl. The couple was both shocked by this result.
Mrs. Nga advised Mr. D. to bring their child to the hospital for a thorough examination and early intervention. To determine if the child has this syndrome, doctors will rely on information about the patient’s health, test the testicles, reproductive organs, and chest area. Some tests that may be ordered include endocrine hormone tests and chromosome testing.
Normally, each person is born with 46 chromosomes, with females having two X chromosomes (XX) and males having one X and one Y chromosome (XY).
After conducting the tests, the doctor concluded that the boy was born with Klinefelter syndrome. People with Klinefelter may have an additional X chromosome in each cell (XXY), some cells may have an extra X chromosome (mosaic Klinefelter syndrome), or occasionally have more than one extra X chromosome (relatively rare).
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